Arian Foster went from nowhere to be found in the 2009 draft to atop the NFL's rushing list in 2010.
The Houston Texans running back led the league with 1,616 yards rushing this season, the highest single-season total for an undrafted player.
But his team failed to make the playoffs, as did winners of other statistical crowns. San Diego Chargers quarterback Philip Rivers overtook Peyton Manning and Drew Brees for the passing title, throwing for 313 yards Sunday to total 4,710 for the season.
The Denver Broncos' Brandon Lloyd had 1,448 yards receiving to lead the league one year after he was inactive for 14 games.